产品货号:
Z38352
中文名称:
TRPM8抗体
英文名称:
Anti-TRPM8 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TRPM8 Antibody |
指标别名 | LTrpC 6;LTRPC6;Trp p8;TRPM8;TRPP8 |
克隆性 | Monoclonal |
检验物种 | human,mouse |
应用范围 | WB,ICC/IF |
基因名称 | TRPM8 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human TRPM8 Activated by icilin,eucalyptol,menthol,cold and modulation of intracellular pH.Involved in menthol sensation.Permeable for monovalent cations sodium,potassium,and cesium and divalent cation calcium. |
实际分子量 | 127KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Transient receptor potential cation channel subfamily M member 8 (TRPM8),also known as the cold and menthol receptor 1 (CMR1),is a protein that in humans is encoded by the TRPM8 gene.TRPM8 is an ion channel,upon activation it allows the entry of Na+ (sodium) and Ca2+ (calcium) ions to the cell that leads to depolarization and the generation of an action potential.The signal is conducted from primary afferents (type C- and A-delta) eventually leading to the sensation of cold and cold pain.The TRPM8 protein is expressed in sensory neurons,and it is activated by cold temperatures and cooling agents,such as menthol and icilin whereas WS-12 and CPS-369 are the most selective agonist of TRPM8. |
Uniprot ID | Q7Z2W7 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 |
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